Expedite CBCT Review
FDA-cleared AI for CBCT that transforms complex scans into clear, actionable 3D insights so every clinician can review, refer, and plan with confidence.
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First-Ever FDA-cleared AI for 3D Radiology
Transforming hundreds of slices into intuitive, color-coded 3D structures, Second Opinion 3D gives clinicians deeper insight into 3D data in minutes — not hours.
3D Clarity for Every Clinician
Pearl color-codes and segments key oral and maxillofacial anatomy, while AI findings surface clinically significant pathology that demands attention.
- Clean, annotated visualizations make complex 3D data digestible and actionable
- FDA-cleared anatomical segmentation color codes key oral-maxillofacial anatomy

Never Miss a Referral
Surface findings that demand a closer look and ensure the right patients get expert care—no second-guessing or delays.
- Spot asymmetries, lesions, and anomalies that warrant referral
- Support referrals with labeled, color-coded 3D visuals
- Clearly communicate clinical rationale to specialists and patients

Fast Results
Customizable Visualizations
Image Control


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Fast, Intuitive Workflow

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Pearl’s newest FDA-cleared innovation brings real-time AI to CBCT imaging, adding a new dimension of radiologic clarity to dental imaging.
FAQ
What is Pearl Second Opinion 3D® and what does it analyze?
Second Opinion 3D® is Pearl’s FDA-cleared AI for cone beam computed tomography (CBCT) analysis — making Pearl the first and only dental AI company with FDA clearance for both 2D and 3D imaging. It automatically segments key anatomy — inferior alveolar canal, mental foramen, maxillary sinus, nasal space, airway, dentition, maxilla, mandible, and pulp system — and detects pathology in 3D, supporting diagnosis and treatment planning across implantology, endodontics, oral surgery, orthodontics, and airway assessment.
What does Second Opinion 3D® detect on CBCT scans?
Second Opinion 3D® detects a broad range of CBCT findings, including broken teeth, large caries, periapical radiolucencies, nonodontogenic cysts, crown and root fractures, peri-implantitis, bone defects, radiopacities, missing teeth, impactions, TMJ anomalies, and carotid artery calcifications. It also delivers color-coded anatomical segmentation that makes complex CBCT volumes faster and clearer to review — turning scans that might take 20+ minutes to interpret into annotated studies clinicians can act on immediately.
How fast is Pearl Second Opinion 3D®?
Most CBCT scans are analyzed in under 40 seconds from upload to insight, and the system runs on a standard dental workstation through a cloud-based web portal — no specialty hardware required. Clinicians can toggle, isolate, and zoom into segmented structures for in-depth review, and customize color-coded labels for their preferred workflow. From CBCT capture to actionable AI insight typically takes under one minute, which is fast enough to support chairside consults and same-visit case acceptance.
How does Second Opinion 3D® support dental implant planning?
Second Opinion 3D® quantifies bone density, measures proximity to vital structures like the inferior alveolar canal and maxillary sinus, identifies pathology that could compromise placement, and visualizes anatomy in color-coded 3D segmentation. That gives implant clinicians faster, more confident planning — without manually tracing anatomy slice by slice — and gives patients clearer case presentations. It also supports endodontic and oral-surgery workflows where 3D context fundamentally changes the treatment plan.
What CBCT systems and dental imaging platforms does Second Opinion 3D® work with?
Second Opinion 3D® works with all DICOM-compliant CBCT and 3D dental imaging formats, including scans from the major cone beam systems used in general practice, OMFS, endodontics, and orthodontics. It runs through a cloud-based web interface, so any standard dental workstation with internet access can submit and review scans. Pearl provides onboarding, video tutorials, live support, and reference guides; no specialized AI training is required to get value from day one.
