Simpler, Faster CBCT Review for Everyday Care
FDA-cleared AI for CBCT that transforms complex scans into clear, actionable 3D insights so every clinician can review, refer, and plan with confidence.
Get started






























































First-Ever FDA-cleared AI for 3D Radiology
Transforming hundreds of slices into intuitive, color-coded 3D structures, Second Opinion 3D gives clinicians deeper insight into 3D data in minutes — not hours.
3D Clarity for Every Clinician
Pearl color-codes and segments key oral and maxillofacial anatomy, while AI findings surface clinically significant pathology* that demands attention.
- Clean, annotated visualizations make complex 3D data digestible and actionable
- FDA-cleared anatomical segmentation color codes key oral-maxillofacial anatomy

Expert Radiology and Reports, No Extra Work
Send images to board-certified radiologists and get insurance-compliant imagery with just one click.
- Request referrals for identified asymmetries, lesions, and anomalies
- Support requests with labeled, color-coded 3D visuals and clinical notes
- Export CBCT imagery in 2D formats that insurers can review

Fast Results
One-Click Referrals
Interactive 3D Viewer



Fast, Intuitive Workflow

Join the Waitlist
Pearl’s newest FDA-cleared innovation brings real-time AI to CBCT imaging, adding a new dimension of radiologic clarity to dental imaging.
FAQ
What is Pearl Second Opinion 3D® and how does it help dentists read CBCT scans?
Second Opinion 3D® is Pearl’s FDA-cleared AI for cone beam computed tomography (CBCT) analysis — making Pearl the first and only dental AI company with FDA clearance for both 2D and 3D imaging. It automatically segments key anatomy, including the inferior alveolar canal, maxillary sinus, nasal space, airway, mandible, and individual teeth, so dentists can review complex CBCT scans faster, interpret findings with more confidence, and explain them clearly to patients chairside.
Can Second Opinion 3D detect pathology on CBCT scans?
Yes. Second Opinion 3D includes AI-powered pathology detection covering temporomandibular joint disorder (TMD), carotid artery calcifications, impactions, periapical radiolucency, and sinus radiopacities. This helps providers surface clinically significant findings more efficiently and reduces the risk that something important is overlooked. Pathology detection is currently available in Canada, with regulatory clearances for additional regions pending.
How does Second Opinion 3D® make CBCT imaging easier for patient communication?
Traditional CBCT viewers are built for technical image review, not chairside conversations. Second Opinion 3D® turns complex 3D scans into clear, color-coded visuals patients can actually understand — making it easier to explain findings, strengthen case presentation, and build the trust that leads to case acceptance for more complex treatment plans. Chairside pathology detection is currently available in Canada only, with regulatory clearances for additional regions pending.
Can I request a radiology report directly through Second Opinion 3D®?
Yes. Second Opinion 3D® includes an embedded radiology-report workflow, so providers can request a review from a board-certified oral and maxillofacial radiologist without leaving the platform — no downloading files, uploading scans, or completing separate referral forms. It’s a faster, simpler, and more affordable way to add radiologist review to your practice.
What are the everyday use cases for Second Opinion 3D®?
Second Opinion 3D® fits into everyday practice as well as complex cases. It’s useful during new patient visits for a fuller first conversation, in implant, TMJ, and airway cases where 3D context changes the treatment plan, and for endodontic review. It also makes case presentation easier with visuals patients understand, and converts CBCT findings into 2D images for insurance documentation.
What does Second Opinion 3D® detect on CBCT scans?
Second Opinion 3D® detects a broad range of CBCT findings, including broken teeth, large caries, periapical radiolucencies, nonodontogenic cysts, crown and root fractures, peri-implantitis, bone defects, radiopacities, missing teeth, impactions, TMJ anomalies, and carotid artery calcifications. It also delivers color-coded anatomical segmentation that makes complex CBCT volumes faster and clearer to review — turning scans that might take 20+ minutes to interpret into annotated studies clinicians can act on immediately.
Does Second Opinion 3D® help with CBCT documentation for dental insurance claims?
Yes. Because payors don’t accept full CBCT scans for claim submission, Second Opinion 3D® helps practices convert relevant 3D findings into claim-ready 2D images and documentation. This reduces administrative friction for staff and helps support stronger, more consistent reimbursement outcomes.
How fast is Pearl Second Opinion 3D®?
Most CBCT scans are analyzed in under 40 seconds from upload to insight, and the system runs on a standard dental workstation through a cloud-based web portal — no specialty hardware required. Clinicians can toggle, isolate, and zoom into segmented structures for in-depth review, and customize color-coded labels for their preferred workflow. From CBCT capture to actionable AI insight typically takes under one minute, which is fast enough to support chairside consults and same-visit case acceptance.
How does Second Opinion 3D® support dental implant planning?
Second Opinion 3D® quantifies bone density, measures proximity to vital structures like the inferior alveolar canal and maxillary sinus, identifies pathology that could compromise placement, and visualizes anatomy in color-coded 3D segmentation. That gives implant clinicians faster, more confident planning — without manually tracing anatomy slice by slice — and gives patients clearer case presentations. It also supports endodontic and oral-surgery workflows where 3D context fundamentally changes the treatment plan.
What CBCT systems and dental imaging platforms does Second Opinion 3D® work with?
Second Opinion 3D® works with all DICOM-compliant CBCT and 3D dental imaging formats, including scans from the major cone beam systems used in general practice, OMFS, endodontics, and orthodontics. It runs through a cloud-based web interface, so any standard dental workstation with internet access can submit and review scans. Pearl provides onboarding, video tutorials, live support, and reference guides; no specialized AI training is required to get value from day one.
